DrosDel: An isogenic deficiency kit for Drosophila melanogaster


News:

All DrosDel deletions and FRT insertions are now available from the Drosophila Genetic Resource Center (DGRC) in Kyoto, Japan. Many deletions including the core kit are available now from the Bloomington Stock Center.
Note: these RS3 and RS5 FRT-carrying insertions can be used as docking sites for FLP-mediated transgene remobilisation, using the split white+ marker strategy. For review see Venken and Bellen (2007) Development 134:3571-3584.

The second DrosDel paper describing the deletion collection has now been published in Genetics 177: 615-629. We also made the front cover!

The databases have now been updated to Release 5.1 of the Drosophila genome.

A search engine for FRT-derived deletions (FDDs) can be found here. This is a set of over half a million theoretical deficiencies made by combining the information from the DrosDel collection and the Exelixis sequence data available from Harvard, remapped to release 5.1.

A note has been added here about false positive deletions.

The first DrosDel paper describing the P element collection has now been published in Genetics 167: 797-813.

In collaboration with Kevin Cook at the Bloomington Stock Center, we have constructed new coverage maps which show DrosDel, Exelixis, and cytologically mapped deletions. We hope these maps will provide a useful tool for researchers targetting particular areas of the genome for study. These maps can be found in the Coverage Maps section. Please click on a deletion of interest for further information.



Department of Genetics, University of Cambridge, UK